The following are former Mt. Vernon Mustang players that have played or are currently playing NCAA Division I football:
Chad Greenway
* 2001 graduate of Mt. Vernon High School
* College: University of Iowa Hawkeyes
* 1st Round Selection (17th pick) in the 2006 NFL Draft by the Minnesota Vikings
Mike Steffen
* 2004 graduate of Mt. Vernon High School
* College: South Dakota State University Jackrabbits
Jake Steffen
* 2007 graduate of Mt. Vernon High School
* College: South Dakota State University Jackrabbits